The predictability of events decreases rapidly; forecasts and past experiences as the basis for shaping the future lose their validity and relevance; the world is more complicated than ever. "One size fits all" and "best practice" were yesterday's catchwords, but now, rarely is something clearly or precisely determinable to allow us to use a standard process. The purpose of this research is to guide practitioners to evaluate the difficulties and solution alternatives brought by volatility, uncertainty, complexity, and ambiguity, known as VUCA. This research adopted qualitative research methods to support the practitioners for a more understandable and controllable VUCA world. Twenty managers from five medium-sized enterprises serving in different sectors were interviewed. Managers identified the methods and tools they used to control VUCA and valuable insights regarding VUCA-affected business and management environments. Recommendations that can benefit enterprises from different sectors have been compiled within the research results.